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Transfected Stable Cell Lines

Human GOPC_ROS1 BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0239C
Product Type

Overexpression Stable Cell Lines
Cell Type

Lymphocytes
Species

Human
Host Cell

BAF3
Source Organ

Lymphatic
Disease

Normal
Storage

Liquid Nitrogen

The human GOPC_ROS1 BAF3 Cell Line is widely used for exploring oncogenic fusion protein activity and targeted therapies in cancer research.

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  • Human GOPC_ROS1 BAF3 Cell Line
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human GOPC_ROS1 BAF3 Cell Line

Description

Human GOPC_ROS1 BAF3 Cell Line is a genetically engineered model derived from murine BAF3 cells based on customers’ requirement. This cell line is created by lentiviral-mediated integration of a fusion construct encoding human GOPC-ROS1 into BAF3 host cells. The fusion expression cassette is confirmed and validated at gene level by qRT-PCR. Cells are maintained under low passage (<P20). Target GOPC-ROS1 is a fusion oncogene resulting from chromosomal rearrangement, where the GOPC coiled-coil domain drives constitutive activation of the ROS1 tyrosine kinase. This aberration is observed in glioblastoma and non-small cell lung cancer (NSCLC). AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.

Species

Human
Cat.No

ABC-X0239C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • This model enables mechanistic exploration of GOPC-ROS1-mediated oncogenic signaling, offering a platform for ROS1 inhibitor testing, drug resistance evaluation, and fusion-specific pathway interrogation.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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