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Primary Cells

Human Heme-Oncology Peripheral Blood Mononuclear Cells

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Included Diagnoses: Lymphoma (including Non-Hodgkin and Hodgkin’s Lymphoma, B Cell Lymphoma, Burkitt’s Lymphoma, Diffuse Large B-Cell Lymphoma, Follicular Lymphoma, Mantle Cell Lymphoma), Leukemias (including ALL, CML, CLL), Mulitple Myeloma and others.
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Home | Primary Cells | Human Primary Cells | PBMCs | Human Heme-Oncology Peripheral Blood Mononuclear Cells
Species

Human
Cat.No

ABC-TC4327
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Mononuclear Cell
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Peripheral Blood
Disease

Heme-Oncology
Storage

Liquid Nitrogen
Product Type

Diseased Human Peripheral Blood Mononuclear Cells

Description

Human Heme-Oncology Peripheral Blood Mononuclear Cells are a type of mononuclear cell population derived from peripheral blood, mainly including lymphocytes (T cells, B cells, NK cells) and monocytes. Peripheral blood from patients with hematologic oncology conditions (e.g., leukemia, lymphoma, myeloma) .Round mononuclear cells; suspension growth; weak/no adhesion
.PBMCs play an important role in immune regulation: T/B cells mediate adaptive immunity (antigen recognition, antibody production), NK cells perform natural killing functions, and monocytes can differentiate into macrophages or dendritic cells, participating in antigen presentation and inflammation regulation. PBMCs themselves are non-tumorigenic, but may include malignant cells in the hematologic cancer context. PBMCs reflect immune dysregulation in hematologic cancers, influencing tumor immune escape, inflammation, and immune surveillance.

AcceGen Frozen Cells & Cell Lines 1 vial
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Citation

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Application

  • Human Heme-Oncology Peripheral Blood Mononuclear Cells can be used to study the pathogenesis of hematological malignancies such as lymphoma and leukemia, evaluate drug efficacy, and develop new treatment strategies. For example, when evaluating new antibody drugs for hematological tumors, they can be used as effector cells to detect the antibody-dependent cellular cytotoxicity (ADCC) activity of antibodies

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