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Human Hepatitis B Virus (HBV) Peripheral Blood Mononuclear Cells

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Clinical data may include: Medication (current and historical), Disease severity, Viral load, HB3Ag, HBsAg, IgM, Viral Genotype, Liver enzyme results, Co-infection presence or absence.
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Home | Primary Cells | Human Primary Cells | PBMCs | Human Hepatitis B Virus (HBV) Peripheral Blood Mononuclear Cells
Species

Human
Cat.No

ABC-TC4323
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Mononuclear Cell
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Peripheral Blood
Disease

Hepatitis B Virus
Storage

Liquid Nitrogen
Product Type

Diseased Human Peripheral Blood Mononuclear Cells

Description

Human Hepatitis B Virus (HBV) Peripheral Blood Mononuclear CellsHuman Hepatitis B Virus (HBV) Peripheral Blood Mononuclear Cells (PBMCs) are primary human mononuclear cells isolated from patients with chronic hepatitis B. These PBMCs mainly consist of T cells, B cells, NK cells, and monocytes, isolated via density gradient centrifugation and red blood cell lysis. Morphologically, they are round with suspension growth properties. Functionally, these cells play key roles in immune response and serve as models for studying chronic viral infections. The gene/expression profile reflects immune markers, including CD3, CD4/CD8 (T cells), CD19 (B cells), CD56 (NK cells), and CD14 (monocytes), identified by flow cytometry. They are free of mycoplasma, bacteria, yeast, and fungi and cryopreserved to maintain viability.

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Citation

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Application

  • Peripheral blood mononuclear cells (PBMCs) are commonly applied in research settings. They are extracted from circulating blood and are often employed to assess immune responses. PBMCs have broad utility in trending research areas, for example, multi-omics analysis of PBMCs based on CITE-seq data, PBMC differentiation into cardiac or vascular lineages in vitro. Our products are ideal for establishing an in vitro PBMC differentiation system that allows you to merge molecular biology and cell-based analysis to study the differentiation mechanisms of PBMCs.

Frequently Asked Questions

  • What are Human Hepatitis B Virus (HBV) Peripheral Blood Mononuclear Cells (PBMCs)?

    Human Hepatitis B Virus (HBV) Peripheral Blood Mononuclear Cells (PBMCs) are a subset of white blood cells obtained from the whole blood of individuals with confirmed Hepatitis B status. These cells include various types of lymphocytes (T cells, B cells, NK cells) and monocytes, which play a crucial role in the body’s immune response against diseases.

  • How to isolate Human HBV PBMCs from whole blood?

    Human HBV PBMCs are isolated from whole blood using density gradient centrifugation, a process that separates blood components based on their density. Additionally, red blood cell lysis is performed to remove unwanted cells, ensuring a purified population of PBMCs.

  • Are Human HBV PBMCs useful for research?

    Yes. Human HBV PBMCs are useful for research because they can serve as a reservoir for HBV, potentially leading to chronic infection. They are valuable tools for studying the immune response to HBV, developing diagnostic methods, and creating therapeutic strategies to combat the virus and related immune system disorders.

  • What makes AcceGen’s Human HBV PBMCs a preferred choice for researchers?

    AcceGen’s Human HBV PBMCs are produced in a sterile environment by professional operators, ensuring high-quality standards. They employ advanced cryopreservation techniques to maintain high cell viability after thawing. These factors make AcceGen’s PBMCs reliable and effective for research, diagnostics, and therapeutic development related to HBV and the immune system.

  • What are the key applications of Human HBV PBMCs in scientific research?

    Human HBV PBMCs are used in various research applications, including studying the immune response to HBV, investigating the mechanisms of chronic HBV infection, developing new diagnostic tools, and creating and testing potential therapies for HBV and related immune system diseases.

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