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Transfected Stable Cell Lines

Human HRAS (G13D) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human HRAS (G13D) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0019C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocyte
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human HRAS (G13D) BAF3 Cell Line is a genetically engineered model derived from selected murine Ba/F3 parental cell line based on customers’ requirement. HRAS (G13D) BAF3 mutant cell line is generated by stable integration of exogenous human HRAS gene harboring the G13D point mutation into Ba/F3 host cells using our optimized transduction of lentiviral vectors.
Target
HRAS encodes a member of the RAS GTPase family that regulates cell proliferation and differentiation through the MAPK and PI3K signaling pathways. The G13D mutation results in constitutive activation of HRAS and is implicated in tumorigenesis across several solid cancers, including bladder and thyroid carcinomas. AcceGen offers generation of stable overexpression and RAS-mutant cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The HRAS (G13D) BAF3 Cell Line serves as a powerful tool to investigate RAS mutation-driven oncogenesis and therapeutic sensitivity. This model enables mechanistic studies of downstream MAPK/ERK activation, IL-3-independent transformation, and resistance to RAS pathway inhibitors. It is utilized for drug discovery and validation of anti-RAS therapeutic strategies.

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