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Transfected Stable Cell Lines

Human HRAS (G13R) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human HRAS (G13R) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0326C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human HRAS (G13R) BAF3 Overexpression Cell Line is engineered from Ba/F3 cells by stable lentiviral transduction of human HRAS harboring the G13R mutation. Cells are maintained under low passage (<P20) and validated for expression using qRT-PCR. Target HRAS is a key GTPase in the RAS/RAF/MEK/ERK pathway. The G13R mutation renders HRAS constitutively active, promoting oncogenic signaling. It is associated with cancers such as bladder carcinoma and thyroid cancer. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This cell model is suited for dissecting RAS-dependent oncogenesis and for evaluating the efficacy of novel RAS pathway inhibitors in preclinical settings.

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