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Transfected Stable Cell Lines

Human HRAS (Q61P) BAF3 Cell Line

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Species

Human

Cat.No

ABC-X0024C

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial

Cell Type

Lymphocyte

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO₂

Source Organ

Lymphatic

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

BAF3

Description

Human HRAS (Q61P) BAF3 Cell Line is a genetically engineered model derived from selected murine Ba/F3 parental cell line based on customers’ requirement. HRAS (Q61P) BAF3 mutant cell line is generated by stable integration of exogenous human HRAS gene harboring the Q61P point mutation into Ba/F3 host cells using our optimized transduction of lentiviral vectors.
Target
HRAS encodes a GTP-binding protein that regulates proliferation and differentiation through RAS/RAF/MEK/ERK signaling. The Q61P mutation is a well-characterized activating alteration that locks HRAS in its GTP-bound form, driving oncogenic transformation. It is frequently associated with thyroid, bladder, and skin cancers. AcceGen offers generation of stable overexpression and RAS-mutant cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

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Application

  • For research use only

  • The HRAS (Q61P) BAF3 Cell Line serves as a powerful tool to investigate hyperactive RAS signaling and targeted inhibition. This model enables mechanistic studies of IL-3-independent growth, RAS-driven oncogenesis, and pathway-specific drug responses. It is utilized in anti-RAS therapeutic discovery and resistance mechanism analysis.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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