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Species | Human |
Cat.No | ABC-X0024C |
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Product Category | Transfected Stable Cell Lines |
Size/Quantity | 1 vial |
Cell Type | Lymphocyte |
Shipping Info | Dry Ice |
Growth Conditions | 37 °C, 5% CO₂ |
Source Organ | Lymphatic |
Disease | Normal |
Biosafety Level | 1 |
Storage | Liquid Nitrogen |
Product Type | Overexpression Stable Cell Lines |
Host Cell | BAF3 |
Human HRAS (Q61P) BAF3 Cell Line is a genetically engineered model derived from selected murine Ba/F3 parental cell line based on customers’ requirement. HRAS (Q61P) BAF3 mutant cell line is generated by stable integration of exogenous human HRAS gene harboring the Q61P point mutation into Ba/F3 host cells using our optimized transduction of lentiviral vectors.
Target
HRAS encodes a GTP-binding protein that regulates proliferation and differentiation through RAS/RAF/MEK/ERK signaling. The Q61P mutation is a well-characterized activating alteration that locks HRAS in its GTP-bound form, driving oncogenic transformation. It is frequently associated with thyroid, bladder, and skin cancers. AcceGen offers generation of stable overexpression and RAS-mutant cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
For research use only