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Human IL4Ra_IL2RG 293T Cell Line

  • BSL

    1

  • 88
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human IL4Ra_IL2RG 293T Cell Line
Species

Human
Cat.No

ABC-X0262C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Kidney
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

293T

Description

Human IL4Ra_IL2RG 293T Cell Line is a genetically engineered model based on human embryonic kidney 293T cells, stably co-expressing IL4Ra and IL2RG. Constructs are delivered using lentiviral transduction and validated by qRT-PCR. Cells are maintained at low passage numbers (<P20). Target IL4Ra and IL2RG are receptor subunits critical for interleukin signaling. Their co-expression activates JAK-STAT6 pathways and plays key roles in immune response and allergic inflammation. Abnormal expression is implicated in immune disorders and certain leukemias. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This dual receptor model supports mechanistic studies on interleukin signaling and cytokine-mediated regulation in immune cells. It is ideal for drug screening against JAK/STAT modulators and antibody therapeutics targeting IL pathways.

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