Human Large Intestine Cells, Uncultured

Description

Human Large Intestine Cells, Uncultured, are single-cell suspensions and multicellular aggregates derived from dissociated large intestine tissue. These primary cells include cells from absorptive, goblet, and enteroendocrine compartments, reflecting the cellular complexity of the colonic epithelium. Preserved in an uncultured state, these cells retain enzymatic activity critical for evaluating intestinal drug permeability, nutrient absorption, and mucosal responses. Their mixed cellular composition also supports enrichment or differentiation studies toward specific epithelial lineages under defined conditions, facilitating studies on colonic homeostasis, barrier regulation, and microbiota interaction. This format supports the development of personalized or tissue-mimicking digestive models for pharmacological and toxicological research. Each lot undergoes rigorous screening and isolation procedures and is tested to ensure it is free from contamination by HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.