Human Large Intestine Epithelial Cells

Description

Human Large Intestine Epithelial Cells are primary epithelial cells isolated from healthy human large intestinal tissue. These cells are characterized by a typical cobblestone morphology and exhibit features essential for mucosal barrier function in large intestine. They express epithelial-specific markers such as cytokeratin 20 (CK20), E-cadherin, and CDX2, supporting their origin from the colonic mucosa and their barrier-forming function. Functionally, these cells participate in nutrient absorption, mucus secretion, and immune signaling within the gut epithelium. They are highly relevant to studies of gastrointestinal disorders, including colorectal cancer, ulcerative colitis, and gut microbiome interactions. To ensure the quality of these primary cells, repeated freeze-thaw cycles are not recommended due to the fragile nature of these cells. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.