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Primary Cells

Human Myelodysplastic Syndrome Bone Marrow Mononuclear Cells (Relapsed/Refractory)

  • For research use only

Cat No.

ABC-TC3959
Product Type

Immune Cells
Cell Type

Mononuclear Cell
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Bone Marrow
Disease

Myelodysplastic Syndrome
Storage

Liquid Nitrogen

Bone Marrow is obtained from adult Myelodysplastic Syndrome patients.

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  • Human Myelodysplastic Syndrome Bone Marrow Mononuclear Cells (Relapsed/Refractory)
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Home | Primary Cells | Human Primary Cells | Immune System Primary Cells | Human Myelodysplastic Syndrome Bone Marrow Mononuclear Cells (Relapsed/Refractory)

Description

Human Myelodysplastic Syndrome (MDS) Bone Marrow Mononuclear Cells (Relapsed/Refractory) are isolated from the bone marrow of donors with relapsed or refractory myelodysplastic syndrome (MDS). They are non-passaged and cryopreserved at primary isolation to preserve soluble components relevant to research use. They display a mixed suspension morphology featuring dysplastic erythroid, myeloid, and megakaryocytic components. Functionally, these cells present in vitro characteristics associated with apoptosis resistance, altered hematopoietic differentiation, and leukemia-related transformation profiles. Flow cytometry identifies aberrant expression of stem/progenitor markers (e.g., CD117). Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

Human Myelodysplastic Syndrome Bone Marrow Mononuclear Cells (Relapsed/Refractory), MDS BM-MNCs (RR), Relapsed MDS Bone Marrow MNCs, Refractory Myelodysplastic BM Cells
Species

Human
Cat.No

ABC-TC3959
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Mononuclear Cell
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Bone Marrow
Disease

Myelodysplastic Syndrome
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Immune Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Human Myelodysplastic Syndrome Bone Marrow Mononuclear Cells (Relapsed/Refractory) serve as an in vitro model for investigating MDS-associated cellular and molecular profiles. By analyzing their acquired genetic mutations (e.g., NRAS, FLT3), dysregulated hematopoiesis, and microenvironmental adaptations, researchers can explore molecular pathways associated with drug resistance and leukemic transformation, supporting discovery research and target identification for MDS-related molecular mechanisms.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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