Human Neural Cells, Uncultured

Description

Human Neural Cells, Uncultured are primary cells isolated directly from human neural tissue (e.g., brain or spinal cord) without further expansion in culture, preserving their native biological state. These cells consist of a heterogeneous population, including neurons, astrocytes, and oligodendrocytes, which can be identified by key markers such as β-III tubulin (neurons), GFAP (astrocytes), and MBP (oligodendrocytes). Functionally, these cells play critical roles in electrical signaling, support and insulation, and neurotransmitter regulation. Due to their uncultured nature, they retain authentic gene expression profiles and functional characteristics, making them ideal for studying neurodevelopmental disorders (e.g., autism, epilepsy), neurodegenerative diseases (e.g., Alzheimer’s, Parkinson’s), and neuroinflammation. Compared with established neural cell lines, these uncultured human neural cells more accurately reflect in vivo cellular diversity and physiological states of the nervous system.

Application

• Human Neural Cells, Uncultured can be used as in vitro cell models to study the pathogenesis of neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease. These cells can also be used for drug development and screening to evaluate the efficacy and safety.