For research use only
| Cat No. | ABC-X0311C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Fibroblast |
| Species | Human |
| Host Cell | NIH/3T3 |
| Source Organ | Embryo |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Human NRAS (G12S) NIH/3T3 Cell Line supports research into NRAS-mediated cancer signaling, offering insight into mutation-specific drug sensitivity.
Human NRAS (G12S) NIH/3T3 Cell Line is a stable overexpression model for NRAS G12S in NIH/3T3 fibroblasts. It allows for investigation of Ras pathway modulation by this specific variant.
Target
G12S is an activating NRAS mutation that leads to sustained mitogenic signaling and contributes to cancer progression, particularly in hematologic malignancies.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Human |
| Cat.No | ABC-X0311C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Fibroblast |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO2 |
| Source Organ | Embryo |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | NIH/3T3 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
This cell line is useful for studying RAS mutation-driven phenotypes and for preclinical screening of targeted therapies in vitro.