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Species | Human |
Cat.No | ABC-X0311C |
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Product Category | Transfected Stable Cell Lines |
Size/Quantity | 1 vial |
Cell Type | Fibroblast |
Shipping Info | Dry Ice |
Growth Conditions | 37 °C, 5% CO2 |
Source Organ | Embryo |
Disease | Normal |
Biosafety Level | 1 |
Storage | Liquid Nitrogen |
Product Type | Overexpression Stable Cell Lines |
Host Cell | NIH/3T3 |
Human NRAS (G12S) NIH/3T3 Cell Line is a stable overexpression model for NRAS G12S in NIH/3T3 fibroblasts. It allows for investigation of Ras pathway modulation by this specific variant.
Target
G12S is an activating NRAS mutation that leads to sustained mitogenic signaling and contributes to cancer progression, particularly in hematologic malignancies.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
For research use only