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Transfected Stable Cell Lines

Human NRAS (G13A) NIH/3T3 Cell Line

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Species

Human

Cat.No

ABC-X0308C

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial

Cell Type

Fibroblast

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO2

Source Organ

Embryo

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

NIH/3T3

Description

Human NRAS (G13A) NIH/3T3 Cell Line is a stable NIH/3T3 line expressing the G13A mutant of human NRAS. This variant allows for detailed exploration of altered Ras pathway signaling in a fibroblast context.
Target
NRAS is a small GTPase regulating cell proliferation and survival. The G13A mutation affects the GTP-binding domain, potentially altering downstream signal transduction. It has been identified in certain hematologic and solid tumors.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

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Application

  • For research use only

  • This cell line serves as a model for oncogenic RAS pathway activation, anti-Ras compound testing, and mechanism-based functional assays.

Inquiring Human NRAS (G13A) NIH/3T3 Cell Line

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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