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Transfected Stable Cell Lines

Human NRAS (Q61E) BAF3 Cell Line

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  • 92
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human NRAS (Q61E) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0317C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human NRAS (Q61E) BAF3 Overexpression Cell Line is established by introducing the human NRAS Q61E mutation into Ba/F3 cells using lentiviral vectors. Stable cell lines are maintained under passage number <P20 and validated by qRT-PCR for gene overexpression. Target NRAS is a small GTPase that transduces signals from growth factor receptors to downstream effectors such as MAPK and PI3K pathways. The Q61E mutation abrogates GTPase activity, resulting in sustained activation and cellular transformation. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This cell line is a valuable tool for exploring NRAS-driven leukemogenesis or solid tumor progression and serves as a platform for screening targeted therapies that disrupt RAS signaling.

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