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Transfected Stable Cell Lines

Human NRAS (Q61E) BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0317C
Product Type

Overexpression Stable Cell Lines
Cell Type

Lymphocytes
Species

Human
Host Cell

BAF3
Source Organ

Lymphatic
Disease

Normal
Storage

Liquid Nitrogen

Human NRAS (Q61E) BAF3 Cell Line facilitates study of NRAS mutations in leukemic transformation and the evaluation of MAPK pathway-targeted therapies.

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  • Human NRAS (Q61E) BAF3 Cell Line
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human NRAS (Q61E) BAF3 Cell Line

Description

Human NRAS (Q61E) BAF3 Overexpression Cell Line is established by introducing the human NRAS Q61E mutation into Ba/F3 cells using lentiviral vectors. Stable cell lines are maintained under passage number <P20 and validated by qRT-PCR for gene overexpression. Target NRAS is a small GTPase that transduces signals from growth factor receptors to downstream effectors such as MAPK and PI3K pathways. The Q61E mutation abrogates GTPase activity, resulting in sustained activation and cellular transformation. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.

Species

Human
Cat.No

ABC-X0317C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • This cell line is a valuable tool for exploring NRAS-driven leukemogenesis or solid tumor progression and serves as a platform for screening targeted therapies that disrupt RAS signaling.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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