For research use only
| Cat No. | ABC-TC4006 |
| Product Type | Immune Cells |
| Cell Type | T Cell |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Peripheral Blood |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Human PB CD8+/CD45RA+ Naïve Cytotoxic T Cells enable reliable investigation of naive CTL responses in immune monitoring and immunotherapy development.
Human PB CD8+/CD45RA+ Naïve Cytotoxic T Cells are isolated from peripheral blood mononuclear cells. This process yields a highly purified population of CD8+/CD45RA+ naïve cytotoxic T cells. After primary culture, the cells are cryopreserved. These cells are characterized by CD8 expression, indicating their cytotoxic potential, and CD45RA expression, marking their naïve, undifferentiated state. They are crucial for adaptive immune responses against intracellular pathogens such as viruses and tumor cells. These cells exhibit limited proliferative capacity and should be handled gently, avoiding repeated freeze-thaw cycles during in vitro studies. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | Human PB CD8+/CD45RA+ Naïve Cytotoxic T Cells, Naïve CD8+ T Cells (CD45RA+), PB RA+ CTLs, Resting Cytotoxic T Lymphocytes |
| Species | Human |
| Cat.No | ABC-TC4006 |
| Product Category | Primary Cells |
| Size/Quantity | 1 vial |
| Cell Type | T Cell |
| Growth Mode | Suspension |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Peripheral Blood |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Immune Cells |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Human PB CD8+/CD45RA+ Naïve Cytotoxic T Cells can be used to investigate early-stage immune responses, especially in T cell development and activation. These cells serve as a model to study naive T cell priming, differentiation into effector cells, and immune memory formation. They are relevant in immunological studies on vaccination, immune tolerance, and response to pathogens or tumors. Their naïve phenotype enables researchers to examine signaling pathways involved in the initiation of cytotoxic T cell immunity.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).