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Primary Cells

Human Pulmonary Art Endothelial Cells-Diabetic Type I

  • For research use only

Cat No.

ABC-TC3771
Product Type

Pulmonary Cells
Cell Type

Endothelial
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Pulmonary Artery
Disease

Normal
Storage

Liquid Nitrogen

Human Pulmonary Artery Endothelial Cells–Diabetic Type I enable diabetic vascular modeling, inflammation analysis, and endothelial dysfunction assays.

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  • Human Pulmonary Art Endothelial Cells-Diabetic Type I
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Home | Primary Cells | Human Primary Cells | Respiratory System Primary Cells | Human Pulmonary Art Endothelial Cells-Diabetic Type I

Description

Human Pulmonary Artery Endothelial Cells (HPAEC), Diabetic Type 1 are primary endothelial cells isolated from pulmonary arteries of donors diagnosed with Type I diabetes. These cells maintain typical cobblestone morphology, form contact-inhibited monolayers in culture and display tightly packed junctions under confluent conditions. They retain endothelial-specific functions such as barrier formation, nitric oxide production, and cytokine responsiveness. They express key endothelial markers, including PECAM-1, VE-cadherin and von Willebrand Factor (vWF). The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

Human Pulmonary Artery Endothelial Cells-Diabetic Type I, Diabetic Type I HPAECs, T1D Pulmonary Artery ECs, Pulmonary Arterial Endothelial Cells (Type I Diabetes)
Species

Human
Cat.No

ABC-TC3771
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Endothelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Pulmonary Artery
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Pulmonary Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Human Pulmonary Artery Endothelial Cells (HPAEC), Diabetic Type 1, also referred to as Human T1D pulmonary artery endothelial cells or Diabetic Type 1 HPAEC, are an in vitro model derived from human diabetic lung endothelial cells. They are widely used to investigate diabetes-induced endothelial dysfunction, oxidative stress, inflammation, and angiogenesis in the pulmonary vasculature. These cells support drug screening, mechanistic studies of diabetic vascular complications, and the development of therapeutic strategies targeting pulmonary hypertension and diabetic vasculopathy.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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