Human Pulmonary Art Sm Mus Cells-Diabetic Type I

Description

Human Pulmonary Art Sm Mus Cells-Diabetic Type I are isolated from the pulmonary artery tissues of patients with Type I diabetes. These cells exhibit morphological characteristics of a long spindle shape or an irregular shape. They express marker proteins such as α-smooth muscle actin (α-SMA). Their core functions include regulating the contraction and relaxation of the pulmonary artery, participating in the inflammatory response of the vascular wall, and maintaining pulmonary circulation homeostasis. Under the stimulation of pro-inflammatory factors like interleukin-6 (IL-6), these cells can undergo proliferation and migration, and mediate vascular remodeling through the JAK/STAT3 signaling pathway. These cells are valuable for studying arterial health in type 1 diabetes and investigating diabetes type 1 effects on pulmonary SMCs. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.