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Primary Cells

Human PV Peripheral Blood Mononuclear Cells (Untreated)

  • BSL

    1

  • 146
PV Peripheral Blood Mononuclear Cells are enriched by separation using Ficoll-Paque density gradient from the peripheral blood. PV-PBMCs are available in untreated and relapsed/refractory stages.
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Home | Primary Cells | Human Primary Cells | PBMCs | Human PV Peripheral Blood Mononuclear Cells (Untreated)
Species

Human
Cat.No

ABC-TC4051
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Mononuclear Cell
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Peripheral Blood
Disease

Polycythemia Vera
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Diseased Human Peripheral Blood Mononuclear Cells

Description

Human PV Peripheral Blood Mononuclear Cells (Untreated) are a type of mononuclear cell population derived from peripheral blood of healthy people or patients. Small, round mononuclear cells, suspension growth typical of PBMCsThese cells are separated from whole blood by density gradient centrifugation (such as Ficoll-Paque), and mainly contain lymphocytes (T cells, B cells, NK cells) and monocytes, while granulocytes and red blood cells are removed.Typical expression of lineage markers—CD3 for T cells, CD19 for B cells, CD56 for NK cells, CD14 for monocytes These cells play a key role in immune regulation, inflammatory response, antigen presentation and adaptive immune response, among which T cells mediate cellular immunity, B cells participate in humoral immunity, and monocytes can differentiate into macrophages or dendritic cells to further regulate immune homeostasis .Functional role in immune regulation, antigen presentation, inflammation, and adaptive immune response

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Application

  • Human PV Peripheral Blood Mononuclear Cells (Untreated) can be used for immunogenicity determination, tumor immunotherapy evaluation, and autoimmune disease mechanism research. For example, by analyzing changes in CD8+ memory T cell subsets to reveal aging-related immune decline, or as effector cells for antibody drug activity detection, they can provide basic data support for immunotherapy

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