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Species | Human |
Cat.No | ABC-TC4339 |
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Product Category | Primary Cells |
Size/Quantity | 1 vial |
Cell Type | Mononuclear Cell |
Shipping Info | Dry Ice |
Growth Conditions | 37 ℃, 5% CO2 |
Source Organ | Peripheral Blood |
Disease | Sarcoma |
Storage | Liquid Nitrogen |
Product Type | Diseased Human Peripheral Blood Mononuclear Cells |
Human Sarcoma Peripheral Blood Mononuclear Cells are immune cells isolated from the peripheral blood of patients with sarcoma, primarily including lymphocytes (T cells, B cells, NK cells) and monocytes. These cells play critical roles in immune surveillance, cytokine production, and antigen presentation, contributing to anti-tumor responses as well as potential tumor microenvironment modulation. In sarcoma, PBMCs may reflect systemic immune activation or suppression, with altered functional profiles in cytokine secretion (e.g., IFN-γ, IL-6) and cytotoxic activity.
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Human Sarcoma Peripheral Blood Mononuclear Cells can be used to study tumor immune mechanisms. As an in vitro test model for evaluating CAR-T cell therapy and immune checkpoint inhibitors (such as PD-1/PD-L1 inhibitors), these cells can also be used to assess the effects of drugs on the activation and function of patient-derived immune cells.