Human Seminal Vesicle Epithelial Cells

Description

Human Seminal Vesicle Epithelial Cells are derived from healthy human seminal vesicle tissue. The seminal vesicles are tubular glands located posterior and inferior to the urinary bladder. Following primary culture, these cells are cryopreserved. Seminal vesicle epithelial cells play an essential role in the secretion of seminal fluid, contributing to sperm viability and motility by providing nutrients and an optimal microenvironment. These epithelial cells form a secretory lining and are involved in hormone-responsive functions. In vitro, seminal vesicle epithelial cells are commonly used in studies related to reproductive physiology, hormonal regulation, and prostate-associated pathologies. These cells do not proliferate indefinitely and cannot be continuously passaged. Repeated freezing and thawing should be avoided during culture.

Application

• HSVECs offer valuable insights into the physiological and pathological functions of the seminal vesicles. They are effective tools for developing disease models for high-throughput and high-content screening applications. Researchers can investigate conditions affecting the seminal vesicles, such as congenital SV cysts, seminal vesiculitis, and neoplasms. Moreover, the invasion of seminal vesicle tissue is often a significant prognostic marker in prostate cancer, highlighting the importance of HSVECs in cancer research and potential therapeutic developments. Their unique properties make HSVECs crucial for advancing our understanding of male reproductive health and related diseases.