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Human SLC34A2_ROS1 (V2098I) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human SLC34A2_ROS1 (V2098I) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0398C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human SLC34A2_ROS1 (V2098I) BAF3 Cell Line is a genetically engineered model derived from selected murine pro-B Ba/F3 parental cell line based on customers’ requirement. SLC34A2_ROS1 (V2098I) BAF3 overexpression cell line is generated by stable integration of an exogenous human SLC34A2-ROS1 fusion gene with the V2098I mutation into BAF3 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
SLC34A2-ROS1 fusion leads to constitutive activation of ROS1 kinase and is implicated in non-small cell lung cancer. The V2098I mutation may influence kinase activity or inhibitor response. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The SLC34A2_ROS1 (V2098I) BAF3 Overexpression Cell Line is ideal for elucidating ROS1 fusion oncogenic mechanisms and testing ROS1-targeted therapies.

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