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Primary Cells

Human Thyroid Cancer Peripheral Blood Mononuclear Cells

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Included Diagnoses: Papillary, Follicular, Medullary and other carcinomas (including all subtypes), Adenocarcinoma (including all subtypes), Squamous Cell Carcinoma (including all subtypes), Neuroendocrine tumors of the thyroid (including all subtypes).
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Home | Primary Cells | Human Primary Cells | PBMCs | Human Thyroid Cancer Peripheral Blood Mononuclear Cells
Species

Human
Cat.No

ABC-TC4322
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Mononuclear Cell
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Peripheral Blood
Disease

hyroid Cancer
Storage

Liquid Nitrogen
Product Type

Diseased Human Peripheral Blood Mononuclear Cells

Description

Human Thyroid Cancer Peripheral Blood Mononuclear Cells are immune cell populations isolated from the peripheral blood of thyroid cancer patients, mainly including lymphocytes (T cells, B cells, NK cells) and monocytes.Typical mononuclear morphology with round lymphocytes and monocytes exhibiting kidney-shaped or lobed nuclei.PBMCs participate in antitumor immune responses, including antigen presentation (monocytes/macrophages), cytotoxicity (NK cells and CD8+ T cells), and antibody secretion (B cells) [1-4]. In thyroid cancer, PBMCs participate in tumor immune surveillance and regulate the tumor microenvironment, but their functions may be inhibited or dysregulated by tumor immune escape mechanisms (such as PD-L1 upregulation, T cell exhaustion). Functional impairment due to tumor immune escape mechanisms affecting cytotoxicity and antigen presentation

AcceGen Frozen Cells & Cell Lines 1 vial
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Citation

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Application

  • Human Thyroid Cancer Peripheral Blood Mononuclear Cells can be used to study the mechanism of tumor immune escape, evaluate the efficacy of immunotherapy, and find biomarkers for disease monitoring. In addition, the analysis of this cell population provides an important basis for the development of immunotherapy strategies for advanced or refractory thyroid cancer.

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