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Species | Human |
Cat.No | ABC-X0078C |
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Product Category | Transfected Stable Cell Lines |
Size/Quantity | 1 vial |
Cell Type | Lymphocyte |
Shipping Info | Dry Ice |
Growth Conditions | 37 °C, 5% CO₂ |
Source Organ | Lymphatic |
Disease | Normal |
Biosafety Level | 1 |
Storage | Liquid Nitrogen |
Product Type | Overexpression Stable Cell Lines |
Host Cell | BAF3 |
Human TNK1 (L600D) BAF3 Cell Line is a genetically engineered model derived from selected murine Ba/F3 parental cell line based on customers’ requirement. TNK1 (L600D) BAF3 mutant cell line is generated by stable integration of exogenous human TNK1 gene harboring the L600D point mutation into Ba/F3 host cells using our optimized transduction of lentiviral vectors.
Target
TNK1 encodes a tyrosine kinase involved in cellular stress response and interferon signaling. The L600D mutation is located in the kinase domain and affects its functional activity. Emerging studies suggest TNK1’s dual role in tumor suppression and inflammatory modulation. AcceGen offers generation of stable overexpression or mutation-bearing cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
For research use only