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Transfected Stable Cell Lines

Human TNK1 (L600D) BAF3 Cell Line

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Species

Human

Cat.No

ABC-X0078C

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial

Cell Type

Lymphocyte

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO₂

Source Organ

Lymphatic

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

BAF3

Description

Human TNK1 (L600D) BAF3 Cell Line is a genetically engineered model derived from selected murine Ba/F3 parental cell line based on customers’ requirement. TNK1 (L600D) BAF3 mutant cell line is generated by stable integration of exogenous human TNK1 gene harboring the L600D point mutation into Ba/F3 host cells using our optimized transduction of lentiviral vectors.
Target
TNK1 encodes a tyrosine kinase involved in cellular stress response and interferon signaling. The L600D mutation is located in the kinase domain and affects its functional activity. Emerging studies suggest TNK1’s dual role in tumor suppression and inflammatory modulation. AcceGen offers generation of stable overexpression or mutation-bearing cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

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Application

  • For research use only

  • The TNK1 (L600D) BAF3 Cell Line serves as a powerful tool to investigate kinase domain mutation effects, cell proliferation, and TNK1-dependent signaling cascades. This model enables IL-3 independent growth assays, apoptotic profiling, and kinase inhibitor evaluation. It is used for cancer biology and drug discovery research.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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