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Human TNK1 (M596D) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human TNK1 (M596D) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0074C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocyte
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human TNK1 (M596D) BAF3 Cell Line is a genetically engineered model derived from selected murine Ba/F3 parental cell line based on customers’ requirement. TNK1 (M596D) BAF3 mutant cell line is generated by stable integration of exogenous human TNK1 harboring the M596D mutation into Ba/F3 host cells using our optimized transduction of lentiviral vectors.
Target
The TNK1 gene encodes a non-receptor tyrosine kinase involved in cell signaling, growth suppression, and immune modulation. The M596D mutation is located in the kinase domain and is reported to influence TNK1’s enzymatic activity and regulatory function. TNK1 is being studied as a tumor suppressor and potential therapeutic target in hematologic malignancies. AcceGen offers generation of stable overexpression or point-mutant cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The TNK1 (M596D) BAF3 Cell Line serves as a powerful tool to investigate kinase domain regulation, cellular stress responses, and TNK1-mediated apoptosis. This model enables mechanistic studies of cytokine-independent proliferation and targeted kinase inhibitor screening. It is utilized in cancer signaling research and functional genomics.

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