Immortalized Human Ear Chondrocytes

Description

Chondrocytes, which reside in articular cartilage, are responsible for secreting type II collagen and other types of collagen as well as non-collagenous extracellular matrix macromolecules. The proliferation and differentiation of chondroblasts are closely related to the development of the vertebrate skeleton. Chondrocytes are capable of secreting and responding to a series of growth factors, including IGF-1 and IL-1. Chondrocytes cultured in vitro serve as useful models for studying cartilage repair and the pathology of arthritis.