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Immortalized Cell Lines

Immortalized Human Hepatocytes

  • For research use only

Cat No.

ABI-TC3500
Product Type

Immortalized Cell Line
Cell Type

Hepatocyte
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Liver
Disease

Normal
Storage

Liquid Nitrogen

IHH cells are great for quick liver tests. Handle them carefully—avoid repeated freezing and thawing for best results.

Product Image
  • Brightfield micrograph of Immortalized Human Hepatocytes, showing adherent growth.
  • Immortalized Human Hepatocytes
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Home | Immortalized Cell Lines | Immortalized Human Hepatocytes

Description

Immortalized Human Hepatocytes are derived from primary human liver cells and genetically engineered to extend their lifespan while retaining key hepatocyte functions. Originating from normal human liver tissue, these cells display polygonal epithelial morphology with abundant cytoplasm and form tight intercellular junctions in culture. These immotalized human cells express characteristic hepatocyte markers, preserving essential metabolic, detoxification, and synthetic activities. These liver cell lines provide valuable models for liver disease research, drug metabolism and toxicity screening, and studies on viral hepatitis infection. Their stable gene expression and functional profiles make them ideal for investigating liver physiology and pathology in vitro.

Species

Human
Cat.No

ABI-TC3500
Product Category

Immortalized Cell Lines
Size/Quantity

1 vial
Cell Type

Hepatocyte
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Liver
Disease

Normal
Storage

Liquid Nitrogen
Product Type

Immortalized Cell Line

Application

  • Immortalized Human Hepatocytes are widely used in drug metabolism and toxicity testing, hepatitis virus infection models, and liver disease research. Their stable phenotype supports high-throughput screening of pharmaceuticals and environmental toxins. Additionally, they are useful for investigating hepatocyte biology, liver fibrosis mechanisms, and gene editing applications targeting hepatic genes.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Frequently Asked Questions

  • What are immortalized human hepatocytes?

    Immortalized human hepatocytes are liver cells that have been genetically modified to proliferate indefinitely. This is typically achieved by introducing specific genes or using viral vectors that prevent the cells from undergoing senescence, thereby allowing continuous cell division and growth. These cells retain many of the functional characteristics of primary hepatocytes, making them valuable for research and therapeutic purposes.

  • How are immortalized human hepatocytes used in research?

    Immortalized human hepatocytes are used extensively in research to study liver function, drug metabolism, and toxicity. They provide a stable and consistent model for investigating hepatic diseases, including hepatitis and liver cancer.

  • What are the benefits of using immortalized human hepatocytes?

    Prolonged Lifespan: They can be cultured for extended periods, providing a consistent and renewable cell source.

    Liver-Specific Functions: They retain many characteristics of primary hepatocytes, such as enzyme activity related to drug metabolism.

    Reproducibility: Their continuous growth allows for reproducible experiments and large-scale studies.

  • What are hepatocytes?

    Hepatocytes are the primary functional cells of the liver, responsible for metabolism, detoxification, bile production, and synthesis of plasma proteins.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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