For research use only
| Cat No. | ABC-TC0478 |
| Product Type | Human Lymphocytes Cell Lines |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Product Code | JM cell, JM cell line |
Explore JM cell line, a vital tool in biomedical research, offering insights into cellular mechanisms and disease modeling for advanced scientific studies.
JM is a human T‑lymphocyte cell line derived from peripheral blood of a 14‑year‑old male patient with acute T‑cell leukemia and is historically linked to the original Jurkat lineage (E6.1 clone). The cells grow in suspension with lymphoblast morphology and express key T‑cell markers such as CD3 and T-cell receptor, consistent with their leukemic phenotype. JM has been extensively used in studies of T-cell signaling, gene expression, and viral susceptibility, including HIV replication models. Cytogenetic profiling shows pseudodiploid chromosomes typical of T-cell leukemia. Metastatic potential or in vivo tumorigenicity has not been broadly characterized. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV‑1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | JM cell, JM cell line |
| Species | Human |
| Cat.No | ABC-TC0478 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Lymphocytes Cell Lines |
JM is used as an in vitro model of human acute T‑cell leukemia for investigations of T-cell receptor signaling, lymphoblast proliferation, apoptosis, and immune-oncology mechanisms. It is widely applied in studies of intracellular signaling pathways, transcriptional regulation, and cytokine production in T cells. JM also serves as a model for viral infection studies, including HIV replication and antiviral compound testing, and is employed in drug screening assays to evaluate novel chemotherapeutics targeting T-cell leukemia, as well as in mechanistic studies of leukemogenesis and cellular response to immunomodulatory agents.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
