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| Product Code | KLN 205; KLN205 |
| Species | Mouse |
| Cat.No | ABC-TC0509 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Squamous Cell Cancer |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Lung Cancer Cell Lines |
The KLN-205 is a mouse squamous cell carcinoma derived from Nettesheim lung carcinoma. It exhibits transplantability across various mouse strains, including DBA/2, BDF1, AKD2F1, and BALB/c, although it does not fare well in C3H/He or ICR mice. Remarkably, KLN-205 cells maintain remarkable consistency in growth kinetics, plating efficiency, ultrastructural characteristics, and modal chromosome number, regardless of early or late in vitro passages. Over its more than four-decade existence, this cell line has preserved a remarkably stable, nearly tetraploid karyotype comprising 77-82 chromosomes, with minimal structural chromosomal aberrations, limited to only six derivatives involving chromosomes 2, 3, 5, 9, 10, and/or 19.
Why choose KLN-205 from AcceGen?
KLN-205 cells from AcceGen are distinguished by their exceptional viability and quality. They are incubated under optimal conditions and skillfully cryopreserved by operators, ensuring their integrity. Moreover, these cells undergo rigorous quality control procedures to certify their mycoplasma-free status, guaranteeing their reliability for research purposes.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
The KLN-205 cell line holds significant promise for various research applications. It serves as a valuable tool for screening potential chemotherapeutic agents due to its robust characteristics. Furthermore, KLN-205 represents a versatile model for the study of human squamous cell carcinoma, making it particularly suited for investigating lung cancer as well. Moreover, ongoing molecular genetic characterization of this cell line may uncover additional lung- and/or squamous cell carcinoma-specific alterations, further enhancing its utility in cancer research.
