For research use only
| Cat No. | ABC-TC0509 |
| Product Type | Mouse Lung Cancer Cell Lines |
| Species | Mouse |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Squamous Cell Cancer |
| Product Code | KLN 205; KLN205 |
Utilize KLN-205 mouse squamous carcinoma cells for modeling lung metastasis and evaluating chemotherapeutic agents in preclinical cancer research.
KLN-205 is a murine squamous carcinoma cell line derived from Nettesheim lung tumors in DBA/2 mice. Exhibiting typical epithelial morphology, these cells grow adherently with stable proliferation and plating efficiency across early and late passages. KLN-205 maintains a near-tetraploid karyotype (77–82 chromosomes) with notable genetic stability. The line harbors p53 mutations and retains responsiveness to epithelial growth factors, reflecting key aspects of squamous cell carcinogenesis. KLN-205 demonstrates aggressive in vitro growth and is transplantable in multiple mouse strains, including DBA/2, BDF1, AKD2F1, and BALB/c, while showing limited engraftment in C3H/He and ICR strains. Its consistent tumorigenic potential and well-preserved genetic features make KLN-205 a robust and reliable model for investigating murine lung squamous cell carcinoma biology and therapeutic interventions.
| Product Code | KLN 205; KLN205 |
| Species | Mouse |
| Cat.No | ABC-TC0509 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Squamous Cell Cancer |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Lung Cancer Cell Lines |
The KLN-205 cell line is a valuable tool for cancer research, particularly in screening potential chemotherapeutic agents. It serves as a robust model for studying squamous cell carcinoma, including lung cancer. Ongoing molecular characterization of this line may reveal unique alterations related to lung or squamous cell cancers, further enhancing its utility in drug development and tumor biology.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
