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Tumor Cell Lines

KLN-205

  • BSL

    1

  • 261
Mouse squamous cell carcinoma. Cells produce metastases in the lungs when inoculated intravenously into DBA/2 or BDF1 mice. The cells are a potential model for chemotherapeutic screening.
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Product Code

KLN 205; KLN205

Species

Mouse

Cat.No

ABC-TC0509

Product Category Tumor Cell Lines
Size/Quantity

1 vial

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Disease

Squamous Cell Cancer

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Mouse Lung Cancer Cell Lines

Description

KLN-205KLN-205 is a murine lung cancer cell line originally derived from a mouse squamous cell carcinoma of Nettesheim lung carcinoma. It exhibits epithelial-like morphology and adherent culture properties. The cell line maintains a very stable near-tetraploid karyotype, with 77-82 chromosomes, and few structural chromosomal abnormalities, limited to 6 derivative chromosomes, including chromosomes 2, 3, 5, 9, 10, and/or 19. KLN-205 is also tumorigenic.

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Citation

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Application

  • The KLN-205 cell line is a valuable tool for cancer research, particularly in screening potential chemotherapeutic agents. It serves as a robust model for studying squamous cell carcinoma, including lung cancer. Ongoing molecular characterization of this line may reveal unique alterations related to lung or squamous cell cancers, further enhancing its utility in drug development and tumor biolo

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