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| Product Code | KLN 205; KLN205 |
| Species | Mouse |
| Cat.No | ABC-TC0509 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Squamous Cell Cancer |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Lung Cancer Cell Lines |
KLN-205 is a murine lung cancer cell line originally derived from a mouse squamous cell carcinoma of Nettesheim lung carcinoma. It exhibits epithelial-like morphology and adherent culture properties. The cell line maintains a very stable near-tetraploid karyotype, with 77-82 chromosomes, and few structural chromosomal abnormalities, limited to 6 derivative chromosomes, including chromosomes 2, 3, 5, 9, 10, and/or 19. KLN-205 is also tumorigenic.
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The KLN-205 cell line is a valuable tool for cancer research, particularly in screening potential chemotherapeutic agents. It serves as a robust model for studying squamous cell carcinoma, including lung cancer. Ongoing molecular characterization of this line may reveal unique alterations related to lung or squamous cell cancers, further enhancing its utility in drug development and tumor biolo
