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Product Code | KM H-2; KMH2 |
Species | Human |
Cat.No | ABC-TC0514 |
Product Category | Tumor Cell Lines |
Size/Quantity | 1 vial |
Shipping Info | Dry Ice |
Growth Conditions | 37 ℃, 5% CO2 |
Disease | Lymphoma |
Biosafety Level | 1 |
Storage | Liquid Nitrogen |
Product Type | Human Lymphoma Cell Lines |
KM-H2 cell line is a human Hodgkin lymphoma cell line that was originally isolated in 1974 from the pleural effusion of a 37-year-old man with mixed cellularity Hodgkin’s disease. These cells exhibit a uniform spherical morphology as suspension cells, including both bi- and polynucleated cells. The karyotype of KM-H2 cells is complex and unstable, with a hypotriploid karyotype with 3.5% polyploidy. The cell line shows detectable activity of acid phosphatase and non-specific esterase.
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The KM-H2 cell line plays a key role in the study of human Hodgkin’s lymphoma. It helps researchers identify factors that promote the growth and survival of lymphoma cells and is also instrumental in exploring mechanisms of radioresistance. These applications support the development of more effective treatment strategies for this challenging disease.