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Product Code | NCTC 929; NCTC-929; NCTC929; NCTC-929L; L cell; L cells; L-cell; L-cells; L cell line; L; Strain L-929; L-929; L 929; L929(NCTC); Clone 929;NCTC clone 929 |
Species | Mouse |
Cat.No | ABC-TC0576 |
Product Category | Tumor Cell Lines |
Size/Quantity | 1 vial |
Cell Type | Fibroblast |
Shipping Info | Dry Ice |
Growth Conditions | 37 ℃, 5% CO2 |
Source Organ | Adipose |
Disease | Normal |
Biosafety Level | 1 |
Storage | Liquid Nitrogen |
Product Type | Mouse Fibroblas Lymphocytes Cell Lines |
L929 cells are fibroblast-like, adherent cells derived from the subcutaneous tissue of a 100-day-old male C3H/An mouse. They are commonly used in cytotoxicity and biocompatibility assays, especially in biomaterials and tissue engineering. Due to their sensitivity to TNF, they are valuable for cytokine and inflammation studies. Additionally, their susceptibility to viruses like IBDV makes them useful in virology research, including viral replication and antiviral testing. Cells are APRT+ and HPRT+.
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L929 cells are widely used in biological science due to their versatility and functional relevance. They serve as a standard model for in vitro cytotoxicity assay, aiding in the evaluation of potential adverse effects of various compounds. Additionally, L929 cells serves as an alternative source of macrophage colony-stimulating factors (M-CSF), facilitating research in immunology and cell biology. Moreover, the protein composition found in the L929 supernatant offers valuable insights into the activation state during the differentiation of bone marrow-derived macrophages (BMDMs) Their robust response to stimuli also makes them valuble for research in immunology, inflammation, and drug screening.