For research use only
| Cat No. | ABC-TC0579 |
| Product Type | Human Lymphocytes Cell Lines |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Product Code | LBB7, LB-B7, lb b7 |
Species: human female; Tissue: lymphocyte, B; Pathology: paroxysmal nocturnal hemoglobinuria;
LB B7 is a human B lymphocyte cell line established from a female patient diagnosed with paroxysmal nocturnal hemoglobinuria (PNH), a rare acquired clonal hematopoietic disorder characterized by complement‑mediated hemolysis. The cells grow in suspension culture and display stable lymphocytic morphology typical of mature B cells. LB B7 retains molecular and functional features associated with complement sensitivity, immune dysregulation, and clonal hematopoiesis, making it a relevant in vitro model for studying immune‑mediated hematologic diseases. This cell line has been widely referenced in investigations of complement activation pathways, B‑cell–associated immune responses, and hemolytic mechanisms relevant to PNH and related disorders. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | LBB7, LB-B7, lb b7 |
| Species | Human |
| Cat.No | ABC-TC0579 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Lymphocytes Cell Lines |
LB B7 is suitable for PNH‑related research, including studies on complement‑mediated cytotoxicity, B cell biology, and immune regulation. It can be used as an experimental model for mechanistic studies of hematologic immune disorders, as well as for screening and evaluation of therapeutic agents targeting complement pathways or immune modulation. In addition, LB B7 supports basic research in B‑lymphocyte signaling, clonal expansion, and immune dysfunction associated with acquired hematopoietic diseases.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
