For research use only
| Cat No. | ABC-TC0580 |
| Product Type | Human Lymphocytes Cell Lines |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Product Code | LBF9, LB-F9, lb f9 |
Species: human female; Tissue: lymphocyte, B; Pathology: paroxysmal nocturnal hemoglobinuria;
LB F9 is a human B lymphocyte cell line established from a female patient with paroxysmal nocturnal hemoglobinuria (PNH), a rare acquired hematopoietic disorder characterized by complement-mediated hemolysis. The cells grow in suspension culture and exhibit typical lymphocytic morphology, including small round-cell features and occasional multinucleated cells. LB F9 maintains molecular characteristics relevant to complement sensitivity, clonal B-cell expansion, and immune dysregulation, making it a valuable in vitro model for studying B-cell–mediated hemolytic mechanisms and hematologic immune disorders. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | LBF9, LB-F9, lb f9 |
| Species | Human |
| Cat.No | ABC-TC0580 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Lymphocytes Cell Lines |
LB F9 is suitable for research on paroxysmal nocturnal hemoglobinuria, including studies of complement activation, B-cell biology, and clonal hematopoiesis, as well as investigations of cytokine signaling, apoptosis, B-cell receptor pathways, hematopoietic progenitor dynamics, and preclinical evaluation of complement-targeted or immunomodulatory therapies. It is useful for mechanistic studies of immune-mediated hemolysis and drug evaluation targeting complement pathways or immune modulation. The line can also be applied in broader hematologic and immunologic research focusing on acquired B-cell disorders.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
