For research use only
| Cat No. | ABC-HP029X |
| Product Type | Mouse Primary Cells |
| Cell Type | Monocyte |
| Species | Mouse |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Mouse PBMCs freshly isolated from healthy or disease-model mice, containing T, B, NK cells, used for tumor immunity and autoimmune research.
CD-1 Mouse PBMCs are primarily isolated from peripheral blood of outbred CD-1(ICR) mice by density gradient centrifugation, and contain lymphocytes (such as T cells, B cells and NK cells) and monocytes that maintain native morphology and functionality. These cells play pivotal roles in both innate and adaptive immune responses. For instance, T cells regulate immune reactions through cytokine secretion by CD4⁺ subsets. B cells mediate humoral immunity by producing antibodies and presenting antigens. NK cells exert natural killing functions to clear abnormal cells without prior sensitization. Monocytes can further differentiate into macrophages or dendritic cells, participating in antigen processing and presentation. The outbred nature of CD-1 mice provides genetic diversity comparable to human populations, making them particularly valuable for vaccine development and immunotoxicity studies. These peripheral blood mononuclear cells (PBMCs) obtained through mouse PBMC isolation from CD-1 mouse models, using a mouse PBMC isolation kit, offer a standardized and reproducible system for evaluating immune responses in preclinical studies.
| Species | Mouse |
| Cat.No | ABC-HP029X |
| Product Category | Primary Cells |
| Size/Quantity | 1 vial |
| Cell Type | Monocyte |
| Growth Mode | Suspension |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Normal |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Primary Cells |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
CD1 Mouse PBMCs serve as valuable tools for preclinical immunotoxicity screening of pharmaceuticals and chemicals, providing human-relevant safety data. Researchers utilize these cells for vaccine immunogenicity studies due to their reproducible immune responses. The outbred genetic background makes them particularly suitable for evaluating individual variation in immune responses. These PBMCs are also used in basic immunology research investigating lymphocyte activation, cytokine production, and antigen presentation mechanisms. Additionally, they serve as important controls in studies using genetically modified mouse strains.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
