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Product Code | NB4; NB.4 |
Species | Human |
Cat.No | ABC-TC0725 |
Product Category | Tumor Cell Lines |
Size/Quantity | 1 vial |
Shipping Info | Dry Ice |
Growth Conditions | 37 ℃, 5% CO2 |
Disease | Leukemia |
Biosafety Level | 1 |
Storage | Liquid Nitrogen |
Product Type | Human Leukemia Cell Lines |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
The NB4 cell line holds significant value in molecular studies involving the t(15;17) chromosomal translocation. Its ability to undergo functional maturation into polynuclear cells following retinoic acid (RA) treatment is another major advantage. This characteristic makes NB4 cells a valuable tool for examining how RA signaling influences on hematopoietic proliferation and differentiation, specifically in terms of genes regulated by RA (either activated or suppressed). Furthermore, the NB4 cell line can be utilized to explore the effects of different maturation inducers, growth factors, chemotherapeutic drugs, and even retroviral vectors, enabling a broader understanding of their impact on cellular processes.