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M-07e | ||||
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| Product Name | M-07e | |||
| Price | Get Quote | |||
| Product Code | M-07E; M-O7e; M07-e; M07e; Mo7e; MO7e; M07E; MO7E | |||
| Cat.No | ABC-TC1313 | Species | Human | |
| Size/Quantity | 1 vial | Biosafety Level | 1 | |
| Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
| Description | M-07e cell is a subline of the growth factor-independent cell line M-07, which was established from a 6-month-old girl with acute megakaryoblastic leukemia (AML M7) in 1987. It requires interleukin-3 (IL-3) or granulocyte-macrophage colony-stimulating factor (GM-CSF) for growth. M07e cells respond to multiple cytokines and growth factors and exhibit a round, non-adherent morphology in suspension culture, with some cells showing a spindle-like shape and slight adherence. They can become cytokine-independent within 3-4 weeks of culture, likely due to the outgrowth of independent cells. Why choose M-07e from AcceGen? AcceGen prepared M-07e cells under strict sterile conditions to prevent contamination from pathogens. They exhibit high viability and display healthy growth based on their morphology. The identity of M07e cells can be confirmed using short tandem repeat (STR) analysis, ensuring their authenticity and consistency in research applications. | |||
| Disease | Acute Megakaryoblastic Leukemia | |||
| Recommended Medium And Supplement | RPMI 1640 + 10% FBS | |||
| Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). | |||
| Application | FOR RESEARCH USE ONLY
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| Growth Conditions | 37 ℃, 5% CO2 | |||
| Product Type | Human Leukemia Cell Lines | |||
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M-07e cells have important applications in research. They provide a valuable model for studying AML M7, investigating its mechanisms and potential therapies. Additionally, M07e cells are used to explore megakaryocytopoiesis and thrombopoiesis, particularly in relation to the effect of Thrombopoietin (TPO) on platelet production. Moreover, these cells contribute to understanding how cytokines impact cell proliferation, including studying interleukin receptors’ biochemical properties and post-ligand signaling systems. Overall, M-07e cells contribute to research on AML M7, the role of TPO in megakaryocytopoiesis, and the effects of cytokines on cell growth and signaling pathways.
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