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OSCA-8

Product Name

OSCA-8

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Product Code

OSCA-8; OSCA8; OSA8

Cat.No

ABC-TC5571

Species

Canine

Size/Quantity

1 vial

Shipping Info

Dry ice

Storage

Liquid Nitrogen

Description

OSCA-8, an osteosarcoma cell line, originates from a left-shoulder tumor in a 1-year-old male Rottweiler. It thrives in vitro and gives rise to both orthotopic and heterotopic tumor xenografts in immunodeficient mice. Its gene expression profile aligns with the most aggressive molecular phenotype of osteosarcoma. This type of cancer emerges from primitive transformed cells of mesenchymal origin, demonstrating osteoblastic differentiation and generating malignant osteoid.

 

Why choose OSCA-8 from AcceGen?

OSCA-8 from AcceGen is preferred as a high-quality and highly viable cell product. AcceGen ensures professional handling with optimal incubation conditions. The cells are rigorously tested through STR profiling to eliminate mycoplasma contamination and any presence of mouse, rat, Chinese hamster, or African green monkey contaminants. Additionally, OSCA-8 is authenticated using a canine STR marker, enhancing its credibility and practicality.

Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

The OSCA-8 cell line’s relevance lies in its application to address the challenges of canine osteosarcoma, characterized by high metastasis rates and a grim prognosis. It serves as a valuable tool to examine inhibitor cytotoxicity, elucidate resistance mechanisms against established drugs, and innovate novel therapeutic approaches to induce apoptosis. OSCA-8 contributes significantly to advancing the understanding and management of this aggressive disease in canines.

Growth Conditions

37 ℃, 5% CO2

Product Type

Canine Sarcoma Cell Lines

Product Image

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