Porcine Aortic Endothelial Cells

Description

Porcine Aortic Endothelial Cells are derived from the aorta of healthy, plaque-free pigs and cryopreserved after primary culture. They express markers including von Willebrand factor (vWF), CD34, CD146, and VEGF receptors. These cells are widely used in cardiovascular research to investigate endothelial function, atherosclerosis, and vascular homeostasis. They are particularly useful for testing candidate drugs that may affect endothelial integrity and inflammation, contributing to the development of novel cardiovascular therapies. In addition, these cells are applied in xenotransplantation studies to understand immune rejection and compatibility mechanisms between pig organs and human recipients. These cells exhibit limited proliferative capacity in vitro and should not undergo repeated freeze-thaw cycles during handling. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.