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Tumor Cell Lines

Raji

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RAJI cell line was established from the left maxilla of a 12-year-old African boy with Burkitt lymphoma in 1963.
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Product Code

RAJI; P1-Raji

Species

Human

Cat.No

ABC-TC0924

Product Category Tumor Cell Lines
Size/Quantity

1 vial

Cell Type

Lymphoblast

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Disease

Burkitt’s Lymphoma

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Human Lymphoma Cell Lines

Description

Raji
Raji is a human B lymphocyte cell line derived in 1963 from the peripheral blood of an 11-year-old Nigerian male diagnosed with Burkitt lymphoma. These undifferentiated lymphoblasts are characterized by large floating clusters in suspension, with irregularly indented nuclei, abundant cytoplasm, and clumping ribosomes. Raji cells grow as multicellular aggregates and exhibit typical signs of Burkitt lymphoma, including the hallmark t(8;14)(q24;q32) chromosomal translocation, leading to MYC gene overexpression. They are Epstein-Barr virus (EBV) positive, maintaining a latent viral genome, and serve as a classical model for EBV-associated lymphoid malignancies. The karyotype is complex and highly abnormal. Raji cells are tumorigenic when xenografted into immunodeficient mice. This line provides a valuable system for studying viral oncogenesis, B-cell immunology, and lymphoma pathogenesis.
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Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

  • The Raji cell line is an excellent transfection host for genetic manipulation and research.used extensively in immunology to study immune responses. Moreover, this cell line crucial for studying Burkitt lymphoma cell morphology and virology, aiding in understanding the pathology and behavior of these specific cancer cells.

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