For research use only
| Cat No. | ABC-TC0924 |
| Product Type | Human Lymphoma Cell Lines |
| Cell Type | Lymphoblast |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Burkitt’s Lymphoma |
| Product Code | RAJI; P1-Raji |
Raji human Burkitt lymphoma B cells harbor t(8;14) translocation, EBV-positive, tumorigenic, classic model for viral oncogenesis and lymphoma research.
Raji is a human B lymphocyte cell line established in 1963 from the peripheral blood of an 11-year-old Nigerian male diagnosed with Burkitt lymphoma. These undifferentiated lymphoblasts grow predominantly as large, floating multicellular aggregates in suspension culture, exhibiting irregularly indented nuclei, abundant cytoplasm, and prominent clumping ribosomes. Raji cells harbor the characteristic t(8;14)(q24;q32) chromosomal translocation, resulting in MYC oncogene overexpression, a hallmark of Burkitt lymphoma. They are Epstein-Barr virus (EBV) positive, maintaining the virus in a latent state, making them a classical in vitro model for EBV-associated lymphoid malignancies. The karyotype is complex and highly aneuploid. Raji cells demonstrate tumorigenicity when xenografted into immunodeficient mice. Typical culture features include cellular debris and large cluster formation at high density. This cell line is widely utilized for studying viral oncogenesis, B-cell immunobiology, and lymphoma pathogenesis.
| Product Code | RAJI; P1-Raji |
| Species | Human |
| Cat.No | ABC-TC0924 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Lymphoblast |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Burkitt’s Lymphoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Lymphoma Cell Lines |
The Raji cell line is an excellent transfection host for genetic manipulation and research. They are used extensively in immunology to study immune responses. Moreover, this cell line crucial for studying Burkitt lymphoma cell morphology and virology, aiding in understanding the pathology and behavior of these specific cancer cells.
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Raji is a human B lymphocyte cell line derived from Burkitt’s lymphoma. It is widely used in immunology and cancer research to study B cell function, viral infection, and lymphoma biology.
