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Primary Cells

Rat Colonic Epithelial Cells

  • For research use only

Cat No.

ABC-TC4113
Product Type

Rat Primary Cells
Cell Type

Epithelial
Species

Rat
Growth Conditions

37 ℃, 5% CO2
Source Organ

Colonic
Disease

Normal
Storage

Liquid Nitrogen

Rat Primary Colonic Epithelial Cells from AcceGen are isolated from tissue of 1-day-old neonatal laboratory Sprague–Dawley Rats.

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  • Rat Colonic Epithelial Cells
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Home | Primary Cells | Animal Primary Cells | Rat Primary cells | Rat Colonic Epithelial Cells

Description

Rat Colonic Epithelial Cells (RCEC) are primary cells isolated from the mucosal lining of healthy rat colonic tissue. These epithelial cells play key roles in vital functions such as nutrient absorption, water retention, and the maintenance of epithelial barrier integrity in the gut. RCEC exhibit polygonal, cobblestone-like morphology and form cohesive monolayers through well-developed cell-cell junctions when cultured in vitro. These cells are cryopreserved at an early passage to maintain their original functional characteristics. RCEC are commonly used to study intestinal physiology, inflammation, and gastrointestinal diseases. These cells are characterized by the expression of key epithelial markers such as E-cadherin and cytokeratin. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

Rat Colonic Epithelial Cells, Rat Colon Epithelial Cells, Colonic ECs
Species

Rat
Cat.No

ABC-TC4113
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Epithelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Colonic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Rat Primary Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • RCEC are ideal for in vitro studies in gastrointestinal epithelial biology, including mechanisms underlying intestinal barrier function, permeability, and inflammatory responses. They are widely used to model conditions like colitis, Crohn’s disease, and other inflammatory bowel diseases (IBD). Researchers can explore epithelial responses to cytokines, microbiota, and therapeutic agents that affect gut health using these cells. Additionally, RCEC are valuable for drug screening, particularly for assessing compounds that modulate epithelial repair, inflammation, or immune-epithelial interactions. Therefore, RCEC can be used to investigate factors that influence gut epithelial function and cellular responses relevant to intestinal inflammation and barrier integrity.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Frequently Asked Questions

  • What is the primary function of colonic epithelial cells in the rat colon?

    These cells form a protective barrier in the colon, involved in nutrient absorption and immune defense.

  • How are Rat Colonic Epithelial Cells typically isolated?

    They are usually isolated from rat colon tissue using enzymatic digestion followed by mechanical dissociation.

  • In what types of studies are Rat Colonic Epithelial Cells commonly used?

    They are often used in studies related to gut health, inflammation, cancer research, and barrier function.

  • What are the optimal culture conditions for Rat Colonic Epithelial Cells?

    These cells should be cultured in a specialized medium for epithelial cells, maintained at 37°C with 5% CO2, typically on a collagen or fibronectin-coated surface.

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