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Transfected Stable Cell Lines

Raw264.7/STAT5 Reporter (Luc) Stable Cell Line

  • For research use only

Cat No.

ABC-RC013Y
Product Type

Reporter Stable Cell Lines
Cell Type

Monocyte
Species

Mouse
Host Cell

Raw264.7
Source Organ

Blood / Macrophage
Disease

Leukemia
Storage

Liquid Nitrogen

Raw264.7/STAT5-Luc Reporter Stable Cell Line by AcceGen is for quantitative bioluminescent monitoring of STAT5 signaling in macrophage immune responses.

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  • Raw264.7/STAT5 Reporter (Luc) Stable Cell Line
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Home | Transfected Stable Cell Lines | Raw264.7/STAT5 Reporter (Luc) Stable Cell Line

Description

Raw264.7/STAT5 Reporter (Luc) Stable Cell Line is a macrophage model derived from murine Raw264.7 cells, engineered with a luciferase gene under STAT5-responsive elements. This system retains macrophage functions including cytokine secretion and phagocytosis, and expresses CD14 and F4/80 markers. The luciferase readout enables highly sensitive, quantitative assessment of STAT5 signaling dynamics, suitable for high-throughput drug screening, immune pathway research, and mechanistic studies of inflammation and cancer. All cells are quality-controlled and confirmed free from mycoplasma, fungi, yeast, and bacteria.

Species

Mouse
Cat.No

ABC-RC013Y
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Monocyte
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Blood / Macrophage
Disease

Leukemia
Biosafety Level

2
Storage

Liquid Nitrogen
Product Type

Reporter Stable Cell Lines
Host Cell

Raw264.7
Gene Info

Luciferase (STAT5-responsive reporter)
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The Raw264.7/STAT5 Reporter (Luc) Stable Cell Line enables sensitive bioluminescent monitoring of STAT5 signaling in macrophages. This luciferase-based system quantifies JAK-STAT pathway activation, ideal for high-throughput drug screening and cytokine response studies. It facilitates non-invasive tracking of STAT5 activity in vitro and in vivo, particularly useful for investigating macrophage polarization, tumor microenvironment interactions, and immunotherapy mechanisms. The bioluminescent readout offers superior sensitivity for detecting STAT5-mediated immune responses while eliminating fluorescence interference.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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