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Cell Culture Media, Kits & Reagents

Recombinant Human GM-CSF/CSF2 Protein

  • For research use only

Cat No.

ABC-GF0014

Product Type

Others

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of cytokines with pivotal roles in embryo implantation and subsequent development.

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Description

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of the array of cytokines with pivotal roles in embryo implantation and subsequent development. GM-CSF stimulates the hematopoietic progenitors differentiation into monocytes and neutrophils. GM-CSF can also induce the differentiation of myeloid dendritic cells (DCs) that promote the development of T-helper type 1 (cellular) immune responses in cognate T cells. The active form of the protein is found extracellularly as a homodimer. The encoding gene is localized to a related gene cluster at chromosome region 5q31 which is known to be associated with 5q-syndrome and acute myelogenous leukemia.

Species

Human

Cat.No

ABC-GF0014

Product Category

Cell Culture Media, Kits & Reagents

Size/Quantity

20 µg/100 µg/1 mg

Shipping Info

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Storage

-20°C

Product Type

Others

Concentration

≥ 95 % as determined by SDS-PAGE and SEC-HPLC.

Buffer Mix

Lyophilized from sterile PBS, pH 7.4.
Please contact us for any concerns or special requirements.
Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.

Key Features

< 10 EU per mg of the protein

Quality Control

HPLC-verified. GMP grade is also available

Application

  • GM-CSF/CSF2 is a hematopoietic cytokine, supports in vitro formation of granulocyte-macrophage progenitors. It also induces differentiation of granulocytes, monocytes and macrophages. As a part of the immune or inflammatory cascade, GM-CSF promotes Th1-biased immune responses, angiogenesis, allergic inflammation, and the development of autoimmunity, and is thus worthy of consideration as a therapeutic target.

Inquiring Recombinant Human GM-CSF/CSF2 Protein

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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