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Recombinant Human IL-2 Protein

  • For research use only

Cat No.

ABC-GF0002
Product Type

Others

Interleukin-2 (IL-2) is a T-cell growth factor, produced by T-cells in response to antigenic or mitogenic stimulation, required for T-cell proliferation.

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  • Recombinant Human IL-2 Protein
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Home | Cell Culture Media, Kits & Reagents | Growth Factors & Cytokines | Recombinant Human IL-2 Protein

Description

Interleukin-2 (IL-2), also known as IL2, is a secreted protein that belongs to the IL-2 family. IL-2 was also the first cytokine shown to mediate its effects via a specific IL-2 receptor, and it was also the first interleukin to be cloned and expressed from a complementary DNA (cDNA) library. As a multifunctional cytokine, IL-2 has essential roles in the homeostasis of lymphocytes, including T, B and natural killer (NK) cells. IL-2 is normally produced during an immune response. Antigen binding to the T cell receptor (TCR) stimulates the secretion of IL-2 and the expression of IL-2 receptors IL-2R. The IL-2 / IL-2R interaction then stimulates the growth, differentiation and survival of antigen-selected cytotoxic T cells via the activation of the expression of specific genes.

Species

Human
Cat.No

ABC-GF0002
Product Category

Cell Culture Media, Kits & Reagents
Size/Quantity

20 µg/50 µg/500 µg
Shipping Info

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage

-20°C
Product Type

Others
Concentration

≥ 95 % as determined by SDS-PAGE and SEC-HPLC.
Buffer Mix

Lyophilized from sterile PBS, pH 7.4.
Please contact us for any concerns or special requirements.
Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Key Features

< 5 EU per mg of the protein

Quality Control

HPLC-verified. GMP grade is also available

Application

  • IL-2 can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells and glioma cells, thus IL-2 is widely used for T cell expansion, NK cell activation, and immunotherapy-related cell culture applications.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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