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Recombinant Human IL-6 Protein

  • For research use only

Cat No.

ABC-GF0018
Product Type

Others

Interleukin-6 (IL-6) works as a multifunctional cytokine that plays important roles in regulating immune responses, inflammation, hematopoiesis, etc.

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  • Recombinant Human IL-6 Protein
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Home | Cell Culture Media, kits & Reagents | Growth Factors & Cytokines | Recombinant Human IL-6 Protein

Description

IL-6 (interleukin 6), also known as IL6, is a multifunctional α-helical cytokine that regulates cell growth and differentiation. As a phosphorylated and variably glycosylated molecule, IL-6 protein is secreted by a variety types of cells including T cells and macrophages. It activates through its heterodimeric receptor IL-6 signals through a heterodimeric receptor IL-6R, which expresses gp130 but lacks intrinsic kinase activity. The IL-6/IL-6R/gp130 complex binds IL-6 with high affinity and transduces downstream signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined as an essential role in directing the transition from innate to acquired immunity.

Species

Human
Cat.No

ABC-GF0018
Product Category

Cell Culture Media, kits & Reagents
Size/Quantity

20 µg/100 µg/1 mg
Shipping Info

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage

-20°C
Product Type

Others
Concentration

≥ 95 % as determined by SDS-PAGE
Buffer Mix

Lyophilized from sterile PBS, pH 7.4.
Please contact us for any concerns or special requirements.
Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Key Features

< 10 EU per mg of the protein

Quality Control

GMP grade is also available

Application

  • IL-6 can be developed for use in cell culture, functional assays, and differentiation studies. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined as an essential role in directing the transition from innate to acquired immunity.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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