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Transfected Stable Cell Lines

RPMI-8226/Luciferase Stable Cell Line

  • For research use only

Cat No.

ABC-RC029Y
Product Type

Reporter Stable Cell Lines
Cell Type

B Lymphocyte
Species

Human
Host Cell

RPMI-8226
Source Organ

Peripheral Blood
Disease

Myeloma
Storage

Liquid Nitrogen

RPMI-8226/Luciferase Stable Cell Line by AcceGen for sensitive bioluminescent tracking of multiple myeloma progression and drug response in vivo.

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  • RPMI-8226/Luciferase Stable Cell Line
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Home | Transfected Stable Cell Lines | RPMI-8226/Luciferase Stable Cell Line

Description

RPMI-8226/Luciferase Stable Cell Line is a genetically engineered human multiple myeloma model developed through stable integration of luciferase into RPMI-8226 cells. This engineered cell line maintains characteristic plasma cell morphology and retains native multiple myeloma markers (CD38, CD138) while enabling sensitive, quantitative tracking of tumor progression. The constitutive luciferase expression permits real-time monitoring of tumor growth kinetics, metastatic spread, and treatment response through non-invasive bioluminescence imaging. Particularly valuable for preclinical drug development and metastasis studies, this cell line provides high sensitivity for detecting minimal residual disease in animal models. Cryopreserved at low passage (<P20) to ensure stable reporter expression and genetic integrity. The cells are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast and Bacteria.

Species

Human
Cat.No

ABC-RC029Y
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

B Lymphocyte
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Peripheral Blood
Disease

Myeloma
Biosafety Level

2
Storage

Liquid Nitrogen
Product Type

Reporter Stable Cell Lines
Host Cell

RPMI-8226
Gene Info

Luciferase
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The RPMI-8226/Luciferase Stable Cell Line is an engineered variant of the human multiple myeloma cell line RPMI-8226 with stable luciferase (Luc) expression. This bioluminescent reporter enables sensitive, quantitative tracking of tumor growth and metastasis in both in vitro assays and in vivo xenograft models using D-luciferin substrate. Particularly valuable for high-throughput drug screening and longitudinal therapy monitoring, this cell line provides non-invasive measurement of tumor burden via bioluminescence imaging (BLI). Maintain in standard RPMI-1640 medium with appropriate antibiotic selection.

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High Viability
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