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Transfected Stable Cell Lines

SHC1 Knockout Cell Lysate

  • For research use only

Cat No.

ABC-KC1811
Product Type

CRISPR Knockout Cell Lysate
Species

Human
Host Cell

HEK293T
Storage

Store SHC1 KO Cell Lysate At -20℃. Please Avoid Repeated Freeze-Thaw Cycles.

This gene encodes three main isoforms that differ in activities and subcellular location

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  • SHC1 Knockout Cell Lysate
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Description

This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]

Species

Human
Cat.No

ABC-KC1811
Product Category

Transfected Stable Cell Lines
Size/Quantity

100ug
Growth Mode

Adherent
Shipping Info

Ice Pack
Growth Conditions

37 ℃, 5% CO2
Storage

Store SHC1 KO Cell Lysate At -20℃. Please Avoid Repeated Freeze-Thaw Cycles.
Product Type

CRISPR Knockout Cell Lysate
Host Cell

HEK293T
Stock

Custom

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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