For research use only
| Cat No. | ABC-TC1054 |
| Product Type | Human Lymphoma Cell Lines |
| Cell Type | Lymphocyte-like |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Product Code | VL-51 |
The SLVL Cell Line serves as a valuable model for studying gene expression, cellular responses, and their implications in disease mechanisms.
SLVL (VL51) is a human B-cell lymphoma cell line derived from the peripheral blood of a 70-year-old female patient diagnosed with splenic lymphoma with villous lymphocytes (SLVL), a rare leukemic variant of splenic marginal zone lymphoma. The cells exhibit a lymphocyte-like morphology, grow in suspension. and display characteristic villous projections along the cytoplasmic membrane. SLVL cells display a committed B-cell immunophenotype, expressing CD19, CD20, and surface immunoglobulins. They exhibit clonal rearrangements in the immunoglobulin heavy chain and T-cell receptor β genes and are EBV-positive. These cells provide a valuable model for studying B-cell lymphoproliferative disorders and Ig gene rearrangements.
| Product Code | VL-51 |
| Species | Human |
| Cat.No | ABC-TC1054 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Lymphocyte-like |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Lymphoma Cell Lines |
SLVL (VL51) cells have important roles in elucidating the leukemogenesis of SLVL and diagnosing B-cell disorders. They aid in understanding the underlying mechanisms of splenic lymphoma with circulating villous lymphocytes and uncovering genetic and molecular alterations driving disease. Additionally, the hematological, immunophenotypic, and genomic features of SLVL cells help diagnose and classify various B-cell disorders. By analyzing these cells, researchers gain insights into disease progression, potential therapeutic targets, and refined diagnostic strategies.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
