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TCMK-1

Product Name

TCMK-1

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Product Code

TCMK1; Transformed C3H Mouse Kidney-1

Cat.No

ABC-TC1224

Species

Mouse-Weanling, Mus Musculus

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

The TCMK-1 cell line is a mouse renal tubular cell line originally derived from C3H mouse kidney tissue through SV-40 transformation. These cells exhibit a positive expression of SV40 T-antigen and possess a karyotype model number of 78, while ranging from 64 to 157, with most cells having 2-6 acrocentric chromosomes featuring secondary constrictions, along with 1-4 biarmed chromosomes per cell. Additionally, around 60% of the cells carry one or more minute chromosomes. It is recommended to subculture TCMK-1 cells at a ratio of 1:2 to 1:8 and renew the medium every 2 to 3 days to maintain their growth and viability.

 

Why choose TCMK-1 from AcceGen?

The TCMK-1 cells from AcceGen exhibit high viability and exceptional quality, ensuring reliable research outcomes. These cells are cryopreserved by experienced operators and undergo rigorous quality control measures. When incubated under optimal conditions, TCMK-1 cells provide a robust and dependable platform for various experimental applications.

Disease

Normal

Source Organ

Kidney

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

The TCMK-1 cell line serves as a valuable tool in various research applications related to renal injury, including investigations into mitochondrial injury, hypoxia/reoxygenation injury, and sepsis-induced acute kidney injury. Its utility extends to drug development endeavors aimed at preventing or ameliorating injury and inhibiting renal tubular cell apoptosis. TCMK-1 cells also play a crucial role in elucidating related regulation pathways, thereby supporting the development of alternative treatments for acute kidney injury, making them a pivotal resource in advancing our understanding and management of kidney-related pathologies.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Epithelial

Growth Mode

Adherent

Product Type

Mouse Kidney Cell Lines

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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