| Species |
Human
|
| Cat.No |
ABC-RC047Y
|
| Quality Control |
All cells test negative for mycoplasma, bacteria, yeast, and fungi.
|
| Product Category |
Transfected Stable Cell Lines |
| Size/Quantity |
1 vial
|
| Cell Type |
Monocyte
|
| Shipping Info |
Dry Ice
|
| Growth Conditions |
37 ℃, 5% CO2
|
| Source Organ |
Peripheral Blood
|
| Disease |
Acute Monocytic Leukemia
|
| Biosafety Level |
1
|
| Storage |
Liquid Nitrogen
|
| Product Type |
Reporter Stable Cell Lines
|
| Host Cell |
THP-1
|
| Gene Info |
STAT5 / Luciferase
|
Description
THP-1/STAT5 Reporter (Luc) Stable Cell Line is a human monocytic cell line engineered to monitor STAT5 signaling through luciferase (Luc) expression. Derived from THP-1 cells, it maintains key native THP-1 characteristics, such as the capacity to upregulate CD14 upon differentiation and PMA-induced differentiation into macrophage-like cells, while featuring STAT5-responsive luciferase activity. This reporter system enables sensitive quantification of STAT5 activation by cytokines (IL-2, IL-7, GM-CSF), making it ideal for immunology and hematopoiesis research. The cell line exhibits dose-dependent bioluminescence suitable for high-throughput screening, with stable reporter expression maintained at low passages (<P20). The cells are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, mycoplasma, Fungi, Yeast and Bacteria.
