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| Species | Human |
| Cat.No | ABC-KC2133 |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 100ug |
| Shipping Info | Ice Pack |
| Growth Conditions | 37 ℃, 5% CO2 |
| Storage | Store TNFRSF8 KO Cell Lysate At -20℃. Please Avoid Repeated Freeze-Thaw Cycles. |
| Product Type | CRISPR Knockout Cell Lysate |
| Host Cell | HeLa |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
For research use only